Foundational principles for large scale inference: Illustrations through correlation mining

When can reliable inference be drawn in the "Big Data" context? This paper presents a framework for answering this fundamental question in the context of correlation mining, with implications for general large scale inference. In large scale data applications like genomics, connectomics, and eco-informatics the dataset is often variable-rich but sample-starved: a regime where the number $n$ of acquired samples (statistical replicates) is far fewer than the number $p$ of observed variables (genes, neurons, voxels, or chemical constituents). Much of recent work has focused on understanding the computational complexity of proposed methods for "Big Data." Sample complexity however has received relatively less attention, especially in the setting when the sample size $n$ is fixed, and the dimension $p$ grows without bound. To address this gap, we develop a unified statistical framework that explicitly quantifies the sample complexity of various inferential tasks. Sampling regimes can be divided into several categories: 1) the classical asymptotic regime where the variable dimension is fixed and the sample size goes to infinity; 2) the mixed asymptotic regime where both variable dimension and sample size go to infinity at comparable rates; 3) the purely high dimensional asymptotic regime where the variable dimension goes to infinity and the sample size is fixed. Each regime has its niche but only the latter regime applies to exa-scale data dimension. We illustrate this high dimensional framework for the problem of correlation mining, where it is the matrix of pairwise and partial correlations among the variables that are of interest. We demonstrate various regimes of correlation mining based on the unifying perspective of high dimensional learning rates and sample complexity for different structured covariance models and different inference tasks

On Measure Transformed Canonical Correlation Analysis

In this paper linear canonical correlation analysis (LCCA) is generalized by applying a structured transform to the joint probability distribution of the considered pair of random vectors, i.e., a transformation of the joint probability measure defined on their joint observation space. This framework, called measure transformed canonical correlation analysis (MTCCA), applies LCCA to the data after transformation of the joint probability measure. We show that judicious choice of the transform leads to a modified canonical correlation analysis, which, in contrast to LCCA, is capable of detecting non-linear relationships between the considered pair of random vectors. Unlike kernel canonical correlation analysis, where the transformation is applied to the random vectors, in MTCCA the transformation is applied to their joint probability distribution. This results in performance advantages and reduced implementation complexity. The proposed approach is illustrated for graphical model selection in simulated data having non-linear dependencies, and for measuring long-term associations between companies traded in the NASDAQ and NYSE stock markets

Robust Multiple Signal Classification via Probability Measure Transformation

In this paper, we introduce a new framework for robust multiple signal classification (MUSIC). The proposed framework, called robust measure-transformed (MT) MUSIC, is based on applying a transform to the probability distribution of the received signals, i.e., transformation of the probability measure defined on the observation space. In robust MT-MUSIC, the sample covariance is replaced by the empirical MT-covariance. By judicious choice of the transform we show that: 1) the resulting empirical MT-covariance is B-robust, with bounded influence function that takes negligible values for large norm outliers, and 2) under the assumption of spherically contoured noise distribution, the noise subspace can be determined from the eigendecomposition of the MT-covariance. Furthermore, we derive a new robust measure-transformed minimum description length (MDL) criterion for estimating the number of signals, and extend the MT-MUSIC framework to the case of coherent signals. The proposed approach is illustrated in simulation examples that show its advantages as compared to other robust MUSIC and MDL generalizations